The thrilling and terrifying journey of the Winchester brothers continues as Supernatural enters its 11th season. Sam (Jared Padalecki) and Dean (Jensen Ackles) have spent their lives on the road, battling every kind of supernatural threat. Over the years, after countless bloody adventures, they have faced everything from the yellow-eyed demon that killed their mother to vampires, ghosts, shapeshifters, angels and fallen gods. With the help of allies -- both human and supernatural -- they've discovered that every victory comes with a price. In the show's tenth season, the Winchesters faced their most personal threat yet. The all-powerful Mark of Cain threatened to consume Dean, turning him into one of the monsters he has spent his life hunting. Meanwhile, a formidable witch, Rowena (guest star Ruth Connell), rose to power to claim her position at the right hand of the King of Hell, Crowley (Mark A. Sheppard). Once Rowena revealed herself to be Crowley's mother, the King was forced to choose between his family and the Winchesters -- all while Sam, with the help of fallen angel Castiel (Misha Collins), Crowley, and some unlikely allies, wages a desperate battle to save Dean from the Mark of Cain. Will Sam be able to find a cure for the Mark in time? Will it be enough to save his brother? And a more frightening prospect ... does Dean even want to be saved? Synopsis In the show’s tenth season, Sam and Dean Winchester (Jared Padalecki & Jensen Ackles) faced their most personal threat yet. The all-powerful Mark of Cain threatened to consume Dean, turning him into one of the monsters he has spent his life hunting. Meanwhile, a formidable witch, Rowena (Ruth Connell), rose to power to claim her position at the right hand of the King of Hell, Crowley (Mark A. Sheppard). Once Rowena revealed herself to be Crowley’s mother, the King was forced to choose between his family and the Winchesters — all while Sam, with the help of fallen angel Castiel (Misha Collins), Crowley and some unlikely allies, waged a desperate battle to save Dean from the Mark of Cain. Taking matters into his own hands, Dean paid a terrible price to break free of the curse, but with Death defeated and Darkness freed upon the Earth, the Winchesters will need all the help they can get.