Vince Vaughn and Kevin James headline an all-star comedy from director Ron Howard and producer Brian Grazer about a man who finds out that what you don’t say to a friend is just as important as what you do. Jennifer Connelly, Winona Ryder, Channing Tatum, and Queen Latifah join them in The Dilemma, a story of how far you can bend a brotherly bond before it snaps.

Since college, confirmed bachelor Ronny (Vaughn) and happily married Nick (James) have been through thick and thin. Now partners in an auto design firm, the two pals are vying to land a dream project that would launch their company. With Ronny’s girlfriend, Beth (Connelly), and Nick’s wife, Geneva (Ryder), by their sides, they’re unbeatable.

But Ronny’s world is turned upside down when he inadvertently sees Geneva out with another man and makes it his mission to get answers. As the amateur investigation dissolves his world into comic mayhem, he learns that Nick has a few secrets of his own. Now, with the clock ticking and pressure mounting on the biggest presentation of their careers, Ronny must decide how and when he will reveal the truth to his best friend. Director Ron Howard ( Splash) returns to his comedy roots with The Dilemma, a deft screwball drama-comedy with a decidedly modern spin.

Costars Vince Vaughn (Ronny) and Kevin James (Nick) manage to be funny as well as poignant and their "bromance" is one of the most touching and believable relationships on the big screen. The supporting cast is top-notch too. Jennifer Connelly, effortlessly lovely and graceful, plays Beth, Ronny's girlfriend. Winona Ryder, who makes a welcome return to film, plays Nick's wife, Geneva. "The dilemma" of the title occurs when Ronny sees Geneva with another man.

Should he tell his best friend his wife is cheating on him? And what's the best time to drop a bombshell like that on someone you love? The Dilemma is surprisingly poignant for a comedy--the emotions and heartbreak are faced straight on. And Vaughn and James are more than capable of expanding their doofus personas to show nuance and defeat. The supporting cast, as with all Howard films, is also great--including Channing Tatum as Geneva's partner-in-crime; Queen Latifah, who commands the screen as always, and of course Howard's brother Clint in a cameo.

But the heart of The Dilemma is played out among the four main characters, who are solid, engaging, and sometimes appropriately off-putting. The Dilemma asks "Is honesty really the best policy?" And the answer, deftly portrayed with rueful humor and poignancy, is somewhere between secrets and lies. A.T. Hurley.